The Met Office is warning of power cuts and travel disruption as it issued new weather alerts for snow, sleet and ice lasting right up to the weekend.
Forecasters have put in place yellow weather warnings for large swathes of the country from Thursday until Saturday.
They are warning of ‘some injuries from slips’ as well as falls on icy surfaces.
By the weekend there could be power outages and a further 2cm of snow in some areas.
On Friday there is set to be icy patches on some untreated roads and along pavements and cycle paths.
The weather warning, affecting Scotland and most of England, is for ice throughout the evening and into Friday morning.
In the affected areas there is set to be rain, sleet and snow which will gradually die out, leaving a risk of icy surfaces and ‘difficult travel conditions.’
On Saturday, forecasters have issued a weather warning from 3am until 9pm, covering most of Scotland and the north of England.
There will be a band of ‘heavy snow which may lead to travel disruption.’
Heavy snowfall in West Yorkshire
Detailing the weather forecast the Met Office said there is a small chance of travel delays on roads and some stranded vehicles.
There may also be delayed or cancelled rail and air travel as well as a ‘small chance of power cuts’ and mobile phone coverage outages.
There are also warnings of injuries from slips and falls on icy surfaces.
Forecasters said: “A further 1-2 cm of snow is possible in a few places at first, mainly above 200 metres across Scotland, northern and central England, before residual rain, sleet and snow dies out during Thursday evening.
“Ice is then likely to form on some untreated surfaces, with difficult conditions on some roads and pavements by Friday morning.”
Heavy snow and freezing rain have already battered parts of the UK, with some older patients urged to rebook their coronavirus vaccination appointments to avoid the bad weather.
The Met Office had issued an amber snow warning for parts of Scotland and northern England overnight into Thursday, with up to 11cm falling in the Perth and Kinross area and 5cm in Cumbria by 9am, and large accumulations elsewhere.
Hospital bosses advised older people not to visit Newcastle’s Centre for Life mass vaccination hub due to the conditions, urging them to rebook their appointment.
Earlier, Police Scotland’s road policing unit warned against travelling in the wintry weather.
Chief Superintendent Louise Blakelock said: “Government restrictions on travelling remain in place across Scotland because of the ongoing pandemic.
“People should not leave their homes unless for essential purposes and work from home where possible. The best way to stay safe is to stay at home.
“In the current wintry weather please consider if your journey is exempt under the regulations and also if it really is essential and whether you can delay it until the weather improves.”